Abstract Background The binding sites of sequence specific transcription factors are an important and Missouri Star Patterns relatively well-understood class of functional non-coding DNAs.Although a wide variety of experimental and computational methods have been developed to characterize transcription factor binding sites, they remain difficult to
Abstract Background Colorectal cancer (CRC) presents a complex tumor microenvironment influenced by genetic and microbial factors.Microbial DNA from the gut and tumor microenvironment can translocate into the bloodstream, forming a circulating microbiome associated with prognosis and clinicopathological features.This study investigates the peripher
Maternal diabetes and/or obesity in pregnancy are undoubtedly associated with later disease-risk in the offspring.The placenta, interposed between the mother and the foetus, is a potential mediator of this risk through epigenetic mechanisms, including DNA methylation.In recent years, multiple studies have identified differentially methylated CpG si
In the 1960s Professor Hu Guoding proposed a method of Boomerang measuring information based on the idea that connotation and denotation of a concept satisfies inverse ratio rule.According to this information measure, firstly we put forward the information quantity for information systems and decision systems; then, we discuss Catch the updating me
Dopamine neurotransmission has been ascribed multiple functions with respect to both motivational and associative processes in reward-based learning, though these have proven difficult to tease apart.In order to better describe the role Seat Post of dopamine in associative learning, this series of experiments examined the potential of dopamine D1-